Meta-TDS (Transdermal Delivery System)

Meta-TDS is designated to maximize electroporatioin efficiencies for the Transdermal Delivery System. Through a selected and specific current, ELECTROPORATION impulses lead to a temporary reorganization of the cellular membrane, allowing the creation of new channels through cells and the cellular membrane. These intercellular channels are called as electropores, which facilitates the flow of water-and non water-soluble molecules. The system temporary increases the permeability of the stratum corneum and of the sub layers of the skin. Meta-TDS can thus enhance the penetration of cosmetic solutions to skin tissues easily for passing the active ingredients through follicles, sweat gland and passages.   What is the Electroporation? Electroporation is a phenomenon induced by the application on a biological surface of an electrical impulse capable to generate “electro-pores” inside the lipidic bi-layer of the cell membrane   Physical enhancement technique -       Use the high voltage of 30-1,000V (with aesthetic purpose, it is restricted within 50V) for a short period (10ãÂÂÂÂ?² to 100ms) in contrast to iontophoresis where a low voltage is used. -       Make transient hydrophilic pores (aqueous pathways) across the skin barrier  (Electropore can vary in size from 40-250ãÂÂÂÂ?ÂÂÂÂ?) -        Allow the passage of macromolecules via a combination of diffusion, electrophoresis and electroosmosis. -       Effective for the charged, neutral and even natural molecules, and larger molecules that have their MW up to 40,000 daltons.