Innovative RF Filler Injection System

Introduction of Cellina What i s RF Filler ? - It is combined technology of Radiofrequency wave and Filler injections in one platform, which is an innovative minimally invasive technique for facial rejuvenation. Why RF Filler ? - INNOfill is essentially for facial rejuvenation and for the treatment of scars, stretch marks, and wrinkles combinedly working by RF thermal energy and hyaluronic acid filler. How does it work ? - Monopolar RF treatment has been demonstrated to induce a wound healing response with increased collagen expression and dermal remodeling results in gradual improvement over several months and can be long-lasting, while fillers often result in immediate clinical improvements that are usually temporary. Therefore, a filling/lifting/smoothing effect can be obtained, concerning the effects of aging, and a therapeutic effect occurs on acne scars and striae as well as most of facial rejuvenation. Applications Frequency Power (watt) Needle Light wrinkles & scars 2MHz 3 - 4 30G Mild wrinkles & scars 1MHz 6 - 7 26G Deep wrinkles & scars Incl. lifting effects 1MHz 15(Max) 21G General Parameter of INNOfill Basic theory of RF Filler... INNOfill consists mainly of following two effective performances. Monopolar RF mode - A conducted RF needle, specially formulated to apply radiofrequency is injected into skin and forms 'autologous containment capsule' in order to hold filler longer than ever since the bio-degradation goes slowly. And, Monopolar RF treatment stimulates dermis and helps re-modeling collagen immediately and gradually in long-term. Filler Injection- Soft-tissue filler augmentation is a treatment modality widely used for aesthetic improvement of deep facial lines and wrinkles. However, it is not well accepted for the patients who want longer filler duration. RF Filler - Soft-tissue augmentation and monopolar RF treatment have the potential to restore tissue volume and improve facial laxity. Description 'A'- RF filler is for performing both RF emission and filler injection at same time. - RF only is for performing RF emission only using dedicated needle. 'B' - RF frequency will be selected either 1MHz or, - 2MHz depending on procedures. 'C' - It indicates the status of power and activation of procedures. 'D' - Control button for adjusting each parameters and values by push. 'E' - It shows time that is running currently. 'F' - It controls power level from 1 to 9 levels. How to set INNOfill How does INNOfill works Injecting RF needle into skin using linear retrograde technique with circular movement. Applying RF energy from the end of needle. - Formation of 'autologous containment capsule'- Re-modeling collagen To retrogress needle slowly inserting filler with one of following injection technique according to target. -. Linear / Serial puncture / Cross-hatching / Fan - Soft-tissue augmentation By using these two procedures, a filling/lifting/smoothing effect is therefore obtained, concerning the effects of aging, and a therapeutic effect occurs on acne scars and striae. Advantages of INNOfill Lifting by RF energy and Volume-up by filler can be done in one platform. Long lasting efficacy thanks to RF + Filler technique. Non-invasive procedure thus the lesser down-time. A minimal side-effect by using well known accepted filler procedure. Available customized procedure depend on area to be treated. Expected lifting efficacy additionally by using RF + Filler mode. Reduction of usage of filler because of 'Autologous Containment Capsule'nearly 30%. Result Before Treatment (Day 0) Day 8 Week 4 Week 8   Week 12   WSRS – Wrinkle Severity Rating Scale Grade 1 Grade 2 Grade 3 Grade 4   Grade 5   Grade 1 (absent): - no visible nasolabial fold; continuous skin line Grade 2 (mild): - shallow but visible nasolabial fold with a slight indentation; minor facial feature; implant is expected to produce a slight improvement in appearance Grade 3 (moderate): - moderately deep nasolabial fold; clear facial feature visible at normal appearance but not when stretched; excellent correction is expected from injectable implant Grade 4 (severe): - very long and deep nasolabial fold; prominent facial feature; < 2 mm visible fold when stretched; significant improvement is expected from injectable implant Grade 5 (extreme): - extremely deep and long nasolabial fold, detrimental to facial appearance;2~4mm visivle V-shaped fold when stretched; unlikely to have satisfactory correction with injectable alone Clinical result of INNOfill Objective: - This clinical test is to verify a continuity and a visible volume up of filler stimulated by RF emission Conclusion: Monitoring result in 3 months, it is apparently observed a continuity of volume-up through RF filler treatments compared to the treatment done by only filler procedure. Implication: - Comparing to WSRS based on resting phase, it is scored delta value before and after of filler trt. (reviewer n=8) : deviation = SE (delta) Marked * only on p-value < 0.05 Methods: - RF parameter: frequency-medium, mode-manual, power-15 watt Injected filler 0.5ml (Glytone 3) into nasolabial fold 4 times and forehead fold 2 times On the view of observer, RF Filler injected on left side and only filler on right side n= 3 Macrography on before and after of filler treatment ? completion of test with 3 months monitoring Comparison INNOfill and Spherofill ITEMS SPHEROFILL (Made in Italy, Promo-Italia) INNOFILL (Made in Korea, Amore-pacific) RF Output Voltage (V) Max. 20V (Peak-Peak) Max. 30V (Peak-Peak) RF Output Power (W) Max. 9W (Actual output : approx. 1W) Max. 23W (Actual output : approx. 3W) RF Frequency 1134KHz, 1769KHz Sine Wave 1MHz, 2MHz Sine Wave Display Type LCD type FND type Power Input 100~240V, 50/60Hz 100~240V, 50/60Hz Retail Price Around USD27,000 USD10,000 Needle & Cables Fixed type Detachable (Re-usable) Coating Needle Teflon (Toxic ?) Silicone (Non toxic) Friction of needling Average but PAINFUL Superior and NO-PAIN Grounding patch N/A AMBU Patch Needles 30G / 27G / 26G / 25G / 22G 30G / 27G / 21G Display LCD type - Difficult to read parameters - Hard to set all buttons (double touch) FND type - Easy to read parameters - Convenient to set buttons (one touch)