ExiStation Universal Molecular Diagnostic System(Pd No. : 3003310)

Description:

ExiStation™ Accelerated Clinical Diagnostics Solution is an innovative semi-automated real-time qPCR based molecular diagnostic system. ExiStation™ is a workflow platform consisting of three ExiPrep™ 16 Dx nucleic acid extraction instruments and one Exicycler™ 96 real-time quantitative thermal cycler.

ExiStation™ is able to process on average 36 samples per hour, and is able to handle up to 6 different types of clinical samples within a single run. The system also contains a refrigeration function to preserve the nucleic acids and diagnostic reagents. ExiStation™ is a pipetting-free system that mixes the extracted nucleic acids with the diagnostic reagents automatically, increasing convenience, practicality and reproducibility.

ExiStation™ Manager Software:

ExiStation™ Manager Software is the software interface used to control ExiPrep™ 16 Dx instruments for target nucleic acid extraction and purification from clinical samples, Exicycler™ 96 for amplification and detection of targets via qPCR, and perform analysis post-examination.

After selecting the ExiPrep™ 16 Dx unit desired for use, enter the sample information and select the type of assay you would like to run. The software will automatically select the extraction protocol optimized for the clinical sample type and target nucleic acid type that is selected, and also route qPCR protocol information to the qPCR control software module. Allocate NTCs, PCs and samples and enter sample information (or use the optional barcode reader). After physically loading the samples within the selected ExiPrep™ 16 Dx, initiate extraction. The software will display the elapsed and expected finishing times.

After nucleic acid extraction and purification is complete, ExiPrep™ 16 Dx will automatically pipette the correct amount of eluent in the diagnostic kits that have been placed before the extraction run. The sample information is forwarded to the qPCR control module for a seamless diagnostic workflow. All extracted samples will be listed for allocation to a 96-well plate map. Assign the samples you would like to run, and initiate qPCR for final results within 2 hours.

Workflow Overview:

Medical diagnostics has advanced phenomenally this century with all manner of tests available almost instantly. The finer the ability to conduct various diagnostic tasks is unparalleled in the ExiStation accelerated molecular diagnostic solution from the Bioneer Corporation of Korea. The solution can analyze at the fine diagnostic level of the molecule with various efficiency revisions to the system and your work flow which perform cost, time and attention saving functions so that the end result of the diagnostic solution experience is in essence a refined experience.

The ExiStation is really three timely solutions in one. The platform combines the ExiPrep nucleic acid extraction instruments with the Exicycler real time quantitative thermal cycler, both from Bioneer, to create the innovative, accurate and automated real time diagnostic solution.

The ExiStation has some general benefits for users of the workflow platform. There is great time efficiency available to users of the platform in that the ExiStation is able to process an average of 36 samples per hour. Further, in a single run the system can safely handle six different types of sample. The convenience of refrigeration is built in to the platform so the diagnostic agents and reagents and nucleic acids can be preserved. There is also no requirement to use pipettes with the system as the mixing is conducted automatically thus saving time and resources. The automated mixing is also able to be replicated so that there are no experimental compromises made in the efficiency advances of the platform.

The company has two patent applications underway for the technologies associated with the diagnostics.

In addition to the combination of systems the ExiStation has system management software that represents an advance in itself. The software is for the control of instruments in the ExiPrep sub system and for amplification, detection and the performance of analysis post examination. The entire system is fairly easy to use. One simply selects the ExiPrep unit they want to use and enters information about the sample and the test that is requested. The system’s software conducts a range of automated tasks such as automatically selecting the extraction commands for the sample. The software will display the elapsed and expected time for the conduct of the tasks. The automated actions of the correct amounts of eluent into the diagnostic kits occur after nucleic acid extraction and purification. The information from the sample is fed seamlessly to the qPCR module. It is possible to simply assign tasks and have results within two hours.

Bioneer Corporation was formed in 1992. It had the privileged position of being Korea’s first biotechnology company. The company’s founding stream of investigation was the integration of recombinant DNA technology, fermentation, biochemistry and nucleic acid chemistry in addition to mechanics, photonics and electronics. Bioneer has two facilities within Korea that also engage in production. The Korea based facilities also contain proprietary synthesizers and production lines for oligonucleotide and siRNA synthesis. These days Bioneer also processes recombinant proteins and the company has proprietary purification systems for this.