How supplied
- Potassium Clavulanate
- Potassium Clavulanate + Microcrystalline Cellulose (Avicel)
- Potassium Clavulanate + Silicon Dioxide (Syloid)
[ CEPs available & US DMF filed.
EU GMP(AIFA) & US FDA GMP Certificates availiable. ]
- Amoxicilllin Trihydrate + Potassium Clavulanate ( 2:1/4:1/7:1)
- Molecular structure
- Molecular formula: C8H 8KNO5
- CAS registry number : 61177-45-5
- Molecular weight : 237.3
Specification
1) Appearance : white or almost white, crystalline powder
2) Solubility : freely soluble in water, slightly soluble in alcohol, very slightly soluble in acetone
3) Identification : positive
4) pH of solution : 5.5 ~ 8.0
5) Specific optical rotation : +53° ~ +63°
6) Absorbance : not more than 0.40
7) Water : not more than 0.5%
8) Related substances - any impurity : not more than 1.0 %
totla impurity : not more thatn 2.0 %
9) Assay (as potassium cavulanate) : 96.5% ~ 102.0% (anhydrous substance)
Application : Poassium clavulanate is a potent progressive inhibitor of plasmid-mediated and some β-lactamases producted by Gram-negative bacteria.
Pharmacopoeia quality : EP, USP
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